Aarti Hospital

What is Intracytoplasmic Sperm Injection (ICSI)?

Intracytoplasmic Sperm Injection (ICSI) is a cutting-edge assisted reproductive technique that has revolutionized the treatment of male infertility and certain other fertility challenges. ICSI is a method that helps couples who are having trouble conceiving because of male problems such low sperm count, poor motility, or aberrant morphology. A single sperm is carefully inserted directly into an egg. This accurate microinjection technique is a useful tool in the field of in vitro fertilization (IVF), as it greatly increases the odds of fertilization.

Many couples who are attempting to conceive now have hope thanks to ICSI, but the process is not guaranteed to be successful and should only be explored after speaking with a fertility specialist who can tailor it to each patient's needs.Our dedicated specialists work closely with each individual or couple to tailor this advanced treatment to their unique needs, offering personalized care and support along the way. Your journey to building a family starts here, and we're here to help you every step of the way.

Benefits of Intracytoplasmic Sperm Injection (ICSI)

Treatment for severe male fertility:

ICSI is especially beneficial for couples in which one of the partners has aberrant sperm morphology, low sperm count, or poor sperm motility.

Higher Fertilization Rates:

Because ICSI inserts a sperm directly into the egg, avoiding several obstacles that could prevent fertilization, it has demonstrated higher fertilization rates as compared to standard IVF procedures.

Effective in Resolving Problems Associated with Sperm:

It's helpful in circumstances when the sperm might find it challenging to naturally penetrate the egg. By manually inserting a sperm into the egg, ICSI can get around this obstacle and facilitate fertilization.

Widened Options for Parenthood

ICSI can help couples become parents to biological children even if they were not able to conceive using conventional methods.

Genetic Testing

Preimplantation genetic testing (PGT) can be used in conjunction with (ICSI) to detect genetic problems in embryos prior to implantation, thereby lowering the possibility that the offspring would be born with a genetic condition.

Assistance for Other Fertility concerns

In addition to male infertility, ICSI can be utilized in situations where traditional IVF may not have worked because of problems on the female end, such as past miscarriages, advanced maternal age, or concerns with the eggs.

Control over the Fertilization Process

This accuracy can be useful in a number of situations, guaranteeing conception when it might otherwise be challenging.

What is the Intracytoplasmic Sperm Injection (ICSI) Process?

Ovarian Stimulation

To promote the creation of numerous mature eggs, the female partner usually receives ovarian stimulation with fertility drugs prior to ICSI. By doing this, the likelihood of a successful fertilization and the formation of viable embryos are increased.

Egg extraction

When the eggs are mature, a simple surgical procedure called transvaginal oocyte extraction is used to remove them from the woman's ovaries under anesthesia.

Sperm Collection

The male spouse donates a sample of semen on the same day that the eggs are retrieved. Testicular sperm extraction (TESE) or epididymal sperm aspiration (TESA) may be used to retrieve a sperm sample in certain situations where there are significant male infertility problems, such as obstructive azoospermia.

Egg Preparation

After being carefully recovered, the eggs are cleaned to get rid of any surrounding cells. It is simpler to see and inject a single sperm into each egg with this preparation.

Microinjection

A tiny, hollow needle is used to individually select and immobilize a single sperm under the guidance of a sophisticated microscope and micromanipulation apparatus. Subsequently, the needle is cautiously injected into the cytoplasm of the egg by passing through its outer membrane, or zona pellucida. The egg is directly injected with the sperm.

Fertilization Assessment

Following the injection of sperm, the eggs are incubated and checked for fertilization. Fertilization may usually be verified 16–20 hours following the ICSI process.

Embryo Selection

Throughout the culture phase, the quality and development of the embryos are observed. The intention is to successfully conceive a child by transferring the highest-quality embryos into the woman's uterus.

Embryo Transfer

Two to five days following the ICSI treatment, the woman's uterus receives the selected embryos. A lot of variables, including as the woman's age and medical background, affect how many embryos are transferred. High-quality embryos that are not transplanted but remain viable can be cryopreserved for later use.

Luteal Phase Support:

Hormonal support, such as progesterone, may be given to support the uterine lining and promote embryo implantation following the embryo transfer.

Pregnancy Test

A blood test is performed to ascertain whether pregnancy has taken place 10 to 14 days following the embryo transfer.

Frequently Asked Questions

Couples with severe male infertility—such as low sperm count, poor motility, or irregular sperm shape—are typically candidates for in vitro fertilization (ICSI). Additionally, it may be helpful in situations when prior IVF treatments have failed or where sperm retrieval methods such as testicular or epididymal sperm extraction are required.

In conventional in vitro fertilization (IVF), sperm and eggs are mixed together in a dish so that the sperm can fertilize the eggs on their own. By directly injecting a single sperm into an egg, ICSI removes some of the obstacles to fertilization.

The possible overuse of ICSI, the potential for genetic defects to be passed on, raise certain ethical questions that could lead to decisions about the ethical selection, storage, and disposal of embryos.

Studies indicate that children conceived via in vitro fertilization typically exhibit typical growth and well-being. Studies are still being conducted to ascertain any potential long-term effects.

A number of variables, like as the woman's age, the quality of the embryos, and her previous reproductive history, influence the number of embryos transferred. To reduce the possibility of multiple pregnancies, one to a maximum of two or three embryos may be transferred.

ICSI Treatment in Jalandhar

What is Intracytoplasmic Sperm Injection (ICSI)?